Which medications are associated with increased ADH release?

Nicotine is well-documented to stimulate the release of antidiuretic hormone (ADH), also known as vasopressin. This is primarily due to its effects on the central nervous system and its interactions with neurotransmitter systems. Nicotine can enhance the activity of certain neurons that are involved in the control of ADH secretion, leading to increased levels of this hormone in the bloodstream.

Increased levels of ADH can result in the kidneys retaining more water, which may lead to increased blood volume and can affect blood pressure. This is particularly important in understanding nicotine's impact on fluid balance and cardiovascular function.

While other substances may influence ADH release, nicotine is especially notable for its direct stimulatory effects on ADH secretion as part of its pharmacological action.